Planning

	Mon. 27	Tue. 28	Wed. 29
08:00 09:00 10:00 11:00 12:00 13:00 14:00 15:00 16:00 17:00 18:00 19:00 20:00 21:00 22:00 23:00	Registration 9:00 - 10:20 (1h20) Registration Registration to the BioSynSys conference Welcome messages 10:20 - 10:30 (10min) Welcome messages Amphi Alain Blanchard, Jean-Loup Faulon and Gilles Truan Opening Session 10:30 - 11:20 (50min) Opening Session Amphi › CRISPR tools to engineer and fight Bacteria - Guest Speaker : David Bikard, Institut Pasteur Paris 10:30-11:20 (50min) Genome Engineering 11:20 - 12:00 (40min) Genome Engineering Amphi Alain Blanchard › A CRISPR-based gene drive system to suppress populations of malarial mosquitoes - Guest Speaker : Tony Nolan, Imperial College London 11:20-12:00 (40min) Buffet and poster session #1 12:00 - 14:00 (2h) Buffet and poster session #1 Buffet rooms Genome Engineering 14:00 - 15:00 (1h) Genome Engineering Amphi Alain Blanchard › Impact of donor-recipient phylogenetic distance on bacterial genome transplantation - Fabien Labroussaa, INRA, UMR 1332 BFP 14:00-14:30 (30min) › 3D organization of synthetic and scrambled chromosomes - Heloise Muller, Institut Pasteur 14:30-15:00 (30min) Proteins and Biocatalysts Engineering 15:00 - 15:40 (40min) Proteins and Biocatalysts Engineering Amphi Magali Remaud Siméon › Diversification of Natural and Non-Natural Products Using Engineered Biosynthetic Pathways and Enzymes - Guest Speaker : Jason Micklefield, The University of Manchester 15:00-15:40 (40min) Coffee break 15:40 - 16:20 (40min) Coffee break Buffet rooms Proteins and Biocatalysts Engineering 16:20 - 17:20 (1h) Proteins and Biocatalysts Engineering Amphi Magali Remaud-Siméon › Self-selection using artificial networks: an adaptive tool for directed evolution of enzymes - Adèle Dramé-Maigné, CNRS UMR 7083 Gulliver SPM, CNRS IIS UMI 2820 LIMMS 16:20-16:50 (30min) › Engineering of artificial enzymes toward the construction of a new metabolic pathway for 2,4-di-hydroxybutyric acid production - Yannick Malbert, Toulouse White Biotechnology (TWB), Laboratoire d'Ingénierie des Systèmes Biologiques et des Procédés 16:50-17:20 (30min) Metabolic Engineering 17:20 - 18:00 (40min) Metabolic Engineering Amphi Gilles Truan › Synthetic biosystems for the production of high-value compounds - Guest Speaker : Sotirios Kampranis, University of Copenhagen 17:20-18:00 (40min) Ethics and Societal Issues 18:00 - 19:00 (1h) Ethics and Societal Issues Amphi Gilles Truan › Synthetic biology as a topic for the social sciences and humanities - Guest Speaker: Jane Calvert, University of Edinburgh 18:00-18:40 (40min) Cocktail & Dinner @ Le café français 20:00 - 22:30 (2h30) Cocktail & Dinner @ Le café français Le café Français	Metabolic Engineering 8:50 - 9:50 (1h) Metabolic Engineering Amphi Gilles Truan › A green marine pico-eukaryote to unveil VLC-PUFA pathways - Florence Corellou, Laboratoire de Biogenèse Membranaire - LBM (Bordeaux, France) 08:50-09:20 (30min) › Metabolic engineering of Cupriavidus necator for heterotrophic and autotrophic alka(e)ne production - Lucie Crépin, Laboratoire d'Ingénierie des Systèmes Biologiques et des Procédés 09:20-09:50 (30min) Coffee break 9:50 - 10:30 (40min) Coffee break Biological Networks and Gene Regulation Engineering 10:30 - 12:10 (1h40) Biological Networks and Gene Regulation Engineering Amphi Mathieu Jules › Pseudomonas putida as a cell factory: the software and the hardware - Guest Speaker: Victor de Lorenzo, National Center for Biotechnology Madrid 10:30-11:10 (40min) › Systems metabolic engineering to rebalance nitrogen fixation and nitrogen assimilation in diazotrophs - Jorg Schumacher, Imperial College London 11:10-11:40 (30min) › Molecular basis of membrane protein production and internal membranes proliferation in Escherichia coli - Bruno Miroux, Laboratoire de biologie physico-chimique des protéines membranaires 11:40-12:10 (30min) Buffet and Poster session 12:10 - 14:00 (1h50) Buffet and Poster session Buffet rooms Molecular Programming and Orthogonal Biology 14:00 - 15:40 (1h40) Molecular Programming and Orthogonal Biology Amphi Jean-Loup Faulon › Synthesis of a reaction-diffusion French flag pattern with a molecular program - Guest Speaker : Andre Estevez-Torres, Université Pierre et Marie Curie Paris 14:00-14:40 (40min) › Post-modifications of recombinant elastin-like polypeptides - Elisabeth Garanger, Laboratoire de Chimie des Polymères Organiques 14:40-15:10 (30min) › Expression of a bidomain redox protein containing non-canonical amino acids for selective fluorescence modification and FRET investigations - Robert Quast, Laboratoire d'Ingénierie des Systèmes Biologiques et des Procédés 15:10-15:40 (30min) Coffee break 15:40 - 16:20 (40min) Coffee break Industrial Developments 16:20 - 17:30 (1h10) Industrial Developments Amphi Magali Remaud-Siméon › The Antha Programming Language: Making Biology Simple, Reproducible and Scalable - Guest Speaker : Michael Sadowski, Synthace Ltd. London 16:20-17:00 (40min) › C3P3: first generation of a versatile artificial cytoplasmic expression system that recapitulates mRNA capping and polyadenylation - Philippe Jais, Eukarys SAS 17:00-17:30 (30min) Ethics and Societal Issues 17:30 - 18:30 (1h) Ethics and Societal Issues Amphi Vincent Grégoire Delory Banquet @ Sicambre boat 20:00 - 23:30 (3h30) Banquet @ Sicambre boat Sicambre boat	Integrative and Predictive Biology 9:00 - 10:00 (1h) Integrative and Predictive Biology Amphi Grégory Batt › Prediction uncertainty in the case of unidentifiability and single-cell data – new concepts and methods - Guest Speaker : Gunnar Cedersund, Department of Biomedical Engineering Linköping 09:00-09:40 (40min) › Integrative and predictive biology outside the plant: linking computational tools to fleshy fruit systems - Cécile Cabasson, Université Bordeaux 09:40-10:00 (20min) Coffee break 10:00 - 10:40 (40min) Coffee break Buffet rooms Integrative and Predictive Biology 10:40 - 11:20 (40min) Integrative and Predictive Biology Amphi Grégory Batt › Inference of qualitative rules governing bacterial metabolic configurations under optimal resource allocation - Laurent Tournier, Institut National de la Recherche Agronomique 10:40-11:00 (20min) › Balancing a genetic toggle switch by real-time control or periodic stimulations - Gregory Batt, Inria Saclay - Ile-de-France 11:00-11:20 (20min) CAD for Synthetic Biology 11:20 - 12:00 (40min) CAD for Synthetic Biology Amphi Pablo Carbonell › Multi-Scale Models for Synthetic Circuit Design - Guest Speaker : Joerg Stelling, ETH Zürich 11:20-12:00 (40min) Buffet and poster session #3 12:00 - 13:30 (1h30) Buffet and poster session #3 Buffet rooms CAD for Synthetic Biology 13:30 - 14:30 (1h) CAD for Synthetic Biology Amphi Pablo Carbonell › Automating Engineering Design in Synbio Foundries - Pablo Carbonell, University of Manchester 13:30-14:00 (30min) › Model-based robust design of synthetic designer cells with minimum load for the host cell - Claude Lormeau, Swiss Institute of Bioinformatics, ETH Zürich 14:00-14:30 (30min) Tools and Technologies for Synthetic Biology 14:30 - 16:10 (1h40) Tools and Technologies for Synthetic Biology Amphi Jean-Loup Faulon › Engineering Escherichia coli for specific tumor cell targeting and protein injection - Guest Speaker : Luis Angel Fernández, Centro Nacional de Biotecnología, Madrid 14:30-15:10 (40min) › Metabolic conversions in artificial microcomparments using microfluidics - Thomas Beneyton, CRPP CNRS UPR 8641 15:10-15:40 (30min) › Droplet-Based Microfluidics for Sequential Bottom-Up Assembly of Functional Cell-Like Compartments - Ilia Platzman, Department of Biointerface Science & Technology, Max Planck Institute for Medical Research, Laboratory of Biophysical Chemistry, University of Heidelberg 15:40-16:10 (30min) Closing speeches and prize distribution 16:10 - 16:20 (10min) Closing speeches and prize distribution Amphi Alain Blanchard, Jean-Loup Faulon and Gilles Truan Coffee break 16:20 - 17:00 (40min) Coffee break Buffet rooms

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